Transient systolic murmurs in neonates and premature infants due to mild left (LPA) and right (RPA) pulmonary branch stenosis is recognized but follow up studies are lacking.A total of 32 neonates with murmur and 32 controls were evaluated echocardiographically at baseline and in four months follow up.Diameters of LPA and RPA were smaller in patien
The impact of ketamine on outcomes in critically ill patients: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials
Background This meta-analysis aims to evaluate the effects of ketamine in critically ill intensive care unit (ICU) patients.Methods The search for randomized controlled trials (RCTs) in PubMed, Scopus, and the Cochrane Library was performed initially in January but was repeated in December 2023.Included studies compared ketamine with other traditio
Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue Regeneration
Extracellular vesicles (EVs) are heterogeneous populations of nano- and micro-sized vesicles secreted by various cell types.There is mounting evidence that EVs have widespread roles in transporting proteins, lipids, and nucleic acids between cells and serve as mediators of intercellular communication.EVs secreted from stem cells could function as p
Consumption patterns before and during the COVID-19 pandemic among patients admitted to inpatient drug detoxification treatment: Results of two cross-sectional surveys from 2018 and 2021
BackgroundThe lockdown measures during the SARS-CoV-2 pandemic could have influenced drug consumption patterns of persons with drug use disorder, especially due to a reduced availability of drugs, an increased consumption of sedating substances as a coping strategy, or a shift to novel psychotropic substances (NPS) associated with an increased drug
Predictive factors of drainage volume and drain duration after the inframammary approach to nipple-areolar-complex sparing mastectomy and implant-based breast reconstruction
Background The placement of a closed suction drain is indispensable for preventing serious infections; however, closed suction drains are inevitably accompanied by increases in local infections, pain, and Drill Bit length of hospital stay, and delays in breast cancer treatment including postoperative chemotherapy and radiotherapy.We analyzed predic